Publications

Complete list of publications on PMC

Selected publications

A comprehensive workflow for allele-specific immune gene quantification and expression analysis in single-cell RNA-seq data. Al Ajami A, Schuck J, Marini F, Imkeller K. bioRxiv; 2024. doi: 10.1101/2024.12.10.627679.

Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation. Cakmak P, Lun JH, Singh A, Macas J, Schupp J, Köhler M, Starzetz T, Burger MC, Steidl E, Hasse LM, Hattingen E, Plate KH, Reiss Y, Imkeller K. bioRxiv; 2024. doi: 10.1101/2024.07.04.602038.

Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis. Salamero-Boix A, Schulz M, Anthes J, Mayer J, Möckl A, Tsoukala I, Menger D, Mosa MH, Hetzer J, Macas J, Hehlgans S, Schuck J, Roller B, Reiss Y, Hochart G, Bonnel D, Medyouf H, Rodriguez MB, Broggini T, Czabanka M, Plate KH, Heikenwälder M, Rödel F, Harter PN, Imkeller K, Sevenich L. bioRxiv; 2024. doi: 10.1101/2024.09.30.615883.

CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells. Bexte T, Albinger N, Al Ajami A, Wendel P, Buchinger L, Gessner A, Alzubi J, Särchen V, Vogler M, Rasheed HM, Jung BA, Wolf S, Bhayadia R, Oellerich T, Klusmann JH, Penack O, Möker N, Cathomen T, Rieger MA, Imkeller K, Ullrich E. Nat Commun. 2024 Sep;15(1):8439. doi: 10.1038/s41467-024-52388-1.

Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients. Enssle JC, Campe J, Moter A, Voit I, Gessner A, Yu W, Wolf S, Steffen B, Serve H, Bremm M, Huenecke S, Lohoff M, Vehreschild M, Rabenau HF, Widera M, Ciesek S, Oellerich T, Imkeller K, Rieger MA, von Metzler I, Ullrich E. Leukemia. 2024 Jan;38(1):168-180. doi: 10.1038/s41375-023-02070-0.

BSc and MSc theses

Title Author Degree
Inferring cell-cell interactions in the brain metastasis microenvironment Jens Mayer MSc Bioinformatics (Goethe University)
Development of a multi-layer R object to study immune gene expression in spatial (and single-cell) transcriptomics at allele, gene and functional level Jonas Schuck MSc Bioinformatics (Goethe University)
Linking Adaptive Immune Receptor Repertoires to Spatial Organization of Tumor Infiltrating Lymphocytes Lucie Marie Hasse BSc Bioinformatics (Goethe University)