Publications

Selected publications

Cakmak P, Lun JH, Singh A, Macas J, Schupp J, Köhler M, Starzetz T, Burger MC, Steidl E, Hasse LM, Hattingen E, Plate KH, Reiss Y, Imkeller K. Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation. bioRxiv; 2024. doi: 10.1101/2024.07.04.602038. PPR:PPR878096.

Salamero-Boix A, Schulz M, Anthes J, Mayer J, Möckl A, Tsoukala I, Menger D, Mosa MH, Hetzer J, Macas J, Hehlgans S, Schuck J, Roller B, Reiss Y, Hochart G, Bonnel D, Medyouf H, Rodriguez MB, Broggini T, Czabanka M, Plate KH, Heikenwälder M, Rödel F, Harter PN, Imkeller K, Sevenich L. Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis. bioRxiv; 2024. doi: 10.1101/2024.09.30.615883. PPR:PPR918289.

Bexte T, Albinger N, Al Ajami A, Wendel P, Buchinger L, Gessner A, Alzubi J, Särchen V, Vogler M, Rasheed HM, Jung BA, Wolf S, Bhayadia R, Oellerich T, Klusmann JH, Penack O, Möker N, Cathomen T, Rieger MA, Imkeller K, Ullrich E. CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells. Nat Commun. 2024 Sep;15(1):8439. doi: 10.1038/s41467-024-52388-1. PMID: 39349459; PMCID: PMC11442982.

Köhler M, Reiss Y, Macas J, Cakmak P, Flinner N, Imkeller K, Lun JH, Schupp J, Starzetz T, Moorthy NK, Plate KH, Schulz MH. An AI-based cell segmentation pipeline for studying immune markers from brightfield microscopy images. Research Square; 2024. doi: 10.21203/rs.3.rs-3870252/v1. PPR:PPR792364.

Enssle JC, Campe J, Moter A, Voit I, Gessner A, Yu W, Wolf S, Steffen B, Serve H, Bremm M, Huenecke S, Lohoff M, Vehreschild M, Rabenau HF, Widera M, Ciesek S, Oellerich T, Imkeller K, Rieger MA, von Metzler I, Ullrich E. Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients. Leukemia. 2024 Jan;38(1):168-180. doi: 10.1038/s41375-023-02070-0. PMID: 38049509; PMCID: PMC10776400.

BSc and MSc theses

Title	Author	Degree
Inferring cell-cell interactions in the brain metastasis microenvironment	Jens Mayer	MSc Bioinformatics (Goethe University)
Development of a multi-layer R object to study immune gene expression in spatial (and single-cell) transcriptomics at allele, gene and functional level	Jonas Schuck	MSc Bioinformatics (Goethe University)
Linking Adaptive Immune Receptor Repertoires to Spatial Organization of Tumor Infiltrating Lymphocytes	Lucie Marie Hasse	BSc Bioinformatics (Goethe University)